Casaniemann pick disease

A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered

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Last updated 07 junho 2024
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Researchers from the group Mitochondrial regulation of cell death and steatohepatitis have revealed a new role for acid ceramidase (ACDase) in experimental models and in patients with NPC through the regulation of STARD1 and its impact on mitochondrial function.
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
STARD1 and NPC1 expression as pathological markers associated with astrogliosis in post-mortem brains from patients with Alzheimer's disease and Down syndrome
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells - ScienceDirect
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Lysosomal positioning diseases: beyond substrate storage
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
IJMS, Free Full-Text
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Niemann-Pick disease type C
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
The pathogenesis of Niemann–Pick type C disease: a role for autophagy?, Expert Reviews in Molecular Medicine
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Animals, Free Full-Text
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Early steps in steroidogenesis: intracellular cholesterol trafficking. - Abstract - Europe PMC
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Lysosomal positioning diseases: beyond substrate storage
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
NPC1 - Wikipedia
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
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