Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute

The goal of this project is to elucidate the molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease (NPC). We will investigate the role of protease BACE1, the key Alzheimer's disease (AD) enzyme, in the pathogenesis of NPC disease. We hope that our findings will elucidate BACE1 as a novel target for treating/ameliorating NPC disease.

Solving neurodegeneration: common mechanisms and strategies for

Molecular Mechanisms of Neurological Disease - ScienceDirect

Potential treatment for Niemann-Pick type C, a rare

PDF] Efficient Investigation and Differential Diagnosis of

Silva Katusic Hecimovic - Senior Scientist - Ruđer Bošković

Jasminka ŠTEFULJ, Professor (Full), PhD

PDF) Pharmacological Activation of LXRs Decreases Amyloid-β Levels

Marko Košiček - Science communication coordinator - Ruđer Bošković

Critical role for glycosphingolipids in Niemann-Pick disease type

PDF) Overlapping Neuroimmune Mechanisms and Therapeutic Targets in

Molecular mechanism(s) of cholesterol-effect on APP and BACE1

PDF] Niemann-Pick Type C Disease—Pathophysiology and Future